Don't extrapolate a curve... there's a reason the pump manufacturers stop drawing the curve where they do. If you have to pump at similar flows under both conditions, then install two different pumps - yes, thats means you spend nearly twice as much right off the bat, but if you don't you'll be servicing and replacing the one-size for all conditions pump frequently....
I don't think use of VS pumping will allow similar flow capacities at different head except to the extent that you don't run off the right end of the curve to begin with, so if you are not on the curve at design speed, then no speed adjustment will move you to the left on the new curve.
If your low head pumping needs are occasional, and energy costs are calculated to be inexpensive enough, then induce head on the low head side so you get back on the curve... throttle a valve (which will likely cause cavitation at the valve and slowly disintegrate the valve, but thats cheaper than a pump) or reduce pipe diameter (how much and how far is a calc you can do), or add discharge restrictions....
Have fun.