weirweb:
I have made field adjustments in how a PSV discharge best enters a collection header. I can also state that what you are zeroing in on is a very important detail in the design and operation of PSV's - a subject that is all too often left to others without a firm knowledge of fluid flow (like pipe fitters). I believe any time you spend on making sure you have the most appropriate design in this area is a well-justified effort.
I have tried to stay away from straight, 90 degree entries into the header and I always try to install 45 degree entries. The reason is that I have found it makes a difference in the PSV discharge pressure drop it has to overcome to get into the header. This is especially true for 2-phase flow systems. Additionally, depending on the quality, the design, and the flow rate, the 90 degree entry will tend to errode the header more so than the 45. I realize this is obvious horse sense and I can't explain why many designers haven't considered this - other than they haven't gone thoroughly into the details of fluid flow as you have. Also, I have to admit that it is more economical and space-saving to use the direct, 90 degree entry AND the other factor (as you probably well know) is that construction designers and contractors don't have to worry about running your unit continuously around the clock - they won't be around.
Using a 45 degree entry will use up more real estate and call for a bigger header - at least one to two sizes higher. I don't see a big economic problem with a bigger header (within reasonable length designs) since there isn't much difference in total installed cost between a 10" and a 14" size; however, the 45 degree entries can be a bother and take up a lot of room and pipe fitting. Nevertheless, the benefits from an operating point are there in a 45:
less pressure drop;
less errosion;
less turbulence;
easier flushing action.
I hope this discussion helps you analyze your application.
Art Montemayor
Spring, TX