Minimum clear spacing = (dt + db)/2
Currently looking at an old (1950s) 1-way slab that is only 4" thick (100 mm). Cover is 3/4" with top and bottom steel mats. Not ideal to anchor to, but it spans 10'-0" fairly well. Every other 1/2" diameter bar (reinforcing is 6" oc) is bent to transition from top to bottom reinforcing.