The upstream volume is massive compared to the downstream. The system layout is as follows:
~1200 cubic feet of compressed helium in the form of four 300 cubic foot tanks runs through a manifold that has its own relief valves, check valves, etc. It then exits the manifold and penetrates a building with 1/2" tubing where it connects to a user-operated panel that has an upstream gauge (2400 psig), a downstream gauge (~200 psig), and two PRV's set up in a pilot-valve combination. There is a relief valve downstream of the PRV's as well as a hand valve that is only turned on when the user needs the helium. The volume of tubing downstream of the PRV is orders of magnitude smaller than the tube bank. We are talking 1/2" and 1/4" tubing that may be 5 foot in length at the most. My initial plan of attack was trying to find an equation that involves flow in minus flow out, but then I figured the pressure differential was all I needed to find the flow through the primary PRV since the flow was restricted by the orifice in the PRV anyways.
Using manufacturer flow charts, I computed the maximum flow rate through the PRV using an upstream pressure of 2400 psig and a downstream pressure of 200 psig. This resulted in a flow rate of 600 SCFM. If the PRV and its pilot-PRV fails, this is how much air would be entering the downstream side based solely on the pressure differential. If I understand this correctly, API 520 calcs show that at that flow rate, the relief valve, which has a set orifice size of 0.25", would maintain the downstream pressure at ~243 psig.
However, whats confusing me now is the question of what happens to all of the extra SCFM. If the PRV fails and is constantly introducing 600 SCFM to the system and the RV can only offload so much, then the pressure will constantly build on the downstream side. When the system is functioning properly, then when the PRV introduces too much flow and the pressure builds, the PRV eventually stops the flow and the relief valve will let out some of the helium to maintain the system pressure. What happens if the PRV never stops the flow? How can I determine the resulting pressure or pressurization rate that would occur?
*EDIT: Do the API 520 calcs show that the RV is offloading all 600 SCFM and that it is resulting in a pressure of 243.6 psig?