Just to expand a little...
The for a given mean stress, the fatigue curve can be idealised as
(Cycles To Crack Initiation) = (Constant) * (Alternating Stress) ^ (Beta)
So if you have some factor on stress, you can find the factor on fatigue life as a function of the factor on stress by...
Equation 1:
(Cycles To Crack Initiation 1) = (Constant) * (Alternating Stress 1) ^ (Beta)
Equation 2:
(Cycles To Crack Initiation 2) = (Constant) * (Alternating Stress 2) ^ (Beta)
Equation 3:
(Cycles To Crack Initiation 2) = (Factor On Fatigue Life) * ( Cycles To Crack Initiation 1)
Equation 4:
(Alternating Stress 2) = (Factor on Stress) * (Alternating Stress 1)
Divide Equation 2 by Equation 1:
Cycles To Crack Initiation 2 (Constant) * (Alternating Stress 2) ^ (Beta)
-------------------------------- = ------------------------------------------------------
Cycles To Crack Initiation 1 (Constant) * (Alternating Stress 1) ^ (Beta)
Cycles To Crack Initiation 2
-------------------------------- = ( (Alternating Stress 2) / (Alternating Stress 1) ) ^ (Beta)
Cycles To Crack Initiation 1
Rearrange & substitute Equations 3 & 4 to get:
(Factor On Fatigue Life) = (Factor on Stress) ^ (Beta)
For 2024 aluminium, (Beta) is typically around -5. For 7000-series aluminium alloys, (Beta) can be around -3.5. You need to have good empirical data, measured in the range of stress levels that you are dealing with, for the appropriate temper, bolting conditions, etc, to substantiate your chosen value of (Beta). Obviously, small changes in (Beta) can lead to large differences in (Factor On Fatigue Life), and thus it is good to establish your best estimate of Beta, and then use some conservative value. Conservative values will be different depending on whether you are considering an increase in stress (and thus you want to over-predict the reduction in fatigue life) or decreases in stress (where you want to under-predict the increase in fatigue life). In either case, you want to calculate a new fatigue life that is conservative.
Be wary also when selecting a value of (Beta) if you try to determine the change in stress from a known change in fatigue life.
Other messages in this thread have talked about a 5th power, rather than a -5th power. It just depends on how you treat the change in stress, ie
(Factor on Fatigue Life) = (Factor on Stress) ^ -5 = ( 1 / (Factor on Stress) ) ^ 5
Similar logic leads to analogous rules-of-thumb for use in damage tolerance.
Hope this is useful.