pre-ignition is more of a design flaw and not so much a tuning fault
the amount of heat required to split an exhaust valve is significant, it will take a significant amount of retard to do so not to mention the engine will have to maintain that load for an extended period of time, the only real concern you have for damaged exhaust valves are in truck applications that see heavy loads during towing for extended periods of time, otherwise its null and not even worth mentioning
brian your 13:1 SCR engine shouldn't be ran on anything less than high octane fuel, but its not typical for a gasoline engine with that much compression to be turbocharged, in fact, the upper limit for boosting that i recommend is 10:1 unless you have direct injection which allows you to go higher safely
in any case, you just reiterated what i stated previously, you CAN run your engine with a lower octane fuel but it will require you to pull timing, it IS NOT required that you run higher octane fuel but you do so for safety, regardless of the fuel octane you run, you can typically reach MBT below approx 25% VE then thats when you wreak the benefits of the higher octane
i don't recommend you run your engine with low octane fuel, im just stating that you can
i've ran 450+ rwhp supercharged engines on 87 octane fuel with over 16lbs of boost