Standards are rarely that prescriptive and concentrate on performance requirements compared to strict rules as every system is different. What is required for a simple short atmospheric vent is very different ot a refinery vent system.
What you need to do is demonstrate / calcualte the effect of the reduced diameter on the pressure at the relieving point.
In B 31.3 section K322.6.3 ( a simple search found this) the relief system which includes all the downstream piping needs to be sized such that at your reliving flowrate, the presusre in the thing you're protecting doesnt exceed 110% of the deisgn presusre (116% for multiple reliefs). for a long high flow rate system, 2 1/2" might not be big enough (you need to check) or a short low flow rate, 2" might be good enough. This is called design, not rule following and is why the codes normally don't get too prescriptive, but provide boundaries and limits on things that actually matter like pressure, temperature and flow, not line size.
As an aside, whilst I'm sure 2 1/2" piping exists, I've never come accross it and would prefer 3" if you're going to go for a bigger size.
My motto: Learn something new every day
Also: There's usually a good reason why everyone does it that way