I assume you are using the new Appendix 4. If not, get it, as it changes everything.
Consider an example:
Suppose you have 85 mph 3-second gust, with a tank that is 24' high, 40' diameter.
The lateral wind pressure on the tank shell is 18 PSF x (85/120)^2 = 9.03 PSF. The overturning moment due to that wind pressure is 9.03 PSF x 40' x 24' x 12' to centroid = 104,026 ft-lbs.
The lateral wind pressure on the projected roof area is neglected, per a note there in Addendum 4.
The uplift pressure on the roof is 30 PSF x (85/120)^2 = 15.05 PSF. The uplift force is 15.05 PSF x pi/4 x 40^2 = 18,915 lbs. The moment arm for that force is the tank radius, so the moment is 18,915 ft-lbs x 20' = 378,300 ft-lbs.
Then total overturning moment is 104,026 ft-lbs + 378,300 ft-lbs = 482,326 ft-lbs.
Does that help?
You can compensate for ladders, piping, or stairways in the projected area if you need to.