Sch 40 refers only to the wall thickness of the pipe. As far as material properties, you can find them in the ASTM specification A-53.
I don't think that you can generalize that pipe is more brittle than tube. Cast iron pipe is very brittle, but you mentioned A53 in your question, which is not nearly so.
A-53 specifies chemical composition, tensile requirements, bending requiremdnts, flattening testing, hydrostatic testing, NDT of the weld seam (if present), workmanship, finish and appearance.
A-53 pipe comes in several types - Type F:Furnace-butt welded and continuous welded, Type E:Electric-resistance welded, Grades A and B and Type S:Seamless, grades A and B.
For example, A-53 Type S Grade B would be seamless, open-hearth, electric-furnace or basic-oxygen steel with 0.30% max carbon, 1.20% max Manganese, 0.05% max Phosphorus and 0.06% max Sulfur. The tensile requirements are 60,000 psi min, 35,000 psi yield.
This example is from the 1990 version which has surely been updated. Please get the latest version before proceeding further.
Hope this helps...