cmrazik, please don't be offended at all if I'm off here. I get the impression your boss took on a project involving blast loads, which is probably an area he doesn't have expertise in.
100 psf is a large live load, and is a good blanket design if you're not sure on the live loading on a typical floor. For a blast load though, which is more likely? 100 psf or 100 psi? Does your boss know? Do you?
I went to a SEAOT seminar in Dallas, one of the topics was designing for blast loads. Basically, what I got out of it is that the loading depends on lots of factors, none of which I'm experienced enough with to decide on my own. I'd hire an engineer who can provide you with loading from blast loads. The seminar I went to involved a talk about designing part of the airport in Dallas (DFW) for blast loads. The blast engineers gave the EOR forces which their walls / roof had to resist. I'm sure your project is a much smaller scale, but I'd still be hesitant to do this.
And again, if you or your boss has the experience / knowledge to do this, please don't be offended, and just ignore my uninformed post. But if it is the case that this is out of your area of expertise, don't be afraid to tell your boss you guys need help. I've read several posts on eng-tips.com involving junior engineers asked to do things out of their expertise. One was a boss left a post-tensioned slab on horrible soil for a junior engineer to design while he was gone on vacation. The consensus on here was that the junior engineer should not do the project, and wait until the boss gets back.