Many of the answers thus far have been a circuitous walk in the park, but didn't really touch on the OP's question. :>) This was discussed in a post several years ago. My personal belief is that any friction, whether it's from rifling, wadding, a seal, or what-have-you, is going to reduce velocity, but only very slightly. The explosion taking place to drive the projectile will be "damped" by opposing force (friction), with projectile weight also entering into the equation, and thereby reducing potential velocity. It's simple physics, at this point. Bullet shape, drag coefficients, etc have nothing whatever to do with velocity potential until exiting the muzzle.
However, I have a personal theory that the sudden breakaway of the projectile upon exiting the muzzle, thereby effectively eliminating nearly all friction, has a catapult effect, coupled with the gases created from the propellant actually exceeding the projectile velocity and overtaking the projectile for a brief moment. The physics and math required to prove or disprove my theory are beyond my current understanding, but it could be tested real-world with the right sensors and cameras.
I've spent more than a few hours over the years messing around with ballistics, experimental projectiles and cartridges, and building firearms completely from scratch, and I'll stick to my theory until someone proves it wrong.
It is better to have enough ideas for some of them to be wrong, than to be always right by having no ideas at all.