Your question is not clearly understood. A vacuum pump, no matter what style it is, jet or pump is a compressor. It compresses air (or whatever it is handling) from a low pressure (deep vacuum) to a higher pressure (atmospheric).
Any compressor, therefore has a design flow rate, a design fluid (or combination of fluids if air/water vapor/other non-condensibles for example) and a design starting and ending point.
The pipe sizing is then a function of the fluid flow and pressure losses along the loop.
You haven't been specific about your application, but as an exapmple, for surface condensers for power plant applications, HEI has design parameters that help with vacuum pump sizing.
If you already have a steam ejector, then someone has already done the pipe sizing calculations. If on the other hand you are replacing the steam jets because they are now undersized (in-leakage exceeds original design) then your piping may be as well.
If you don't know your non condensibe rate or air in-leakage rate, you are going to have to put a measuring device on the non condensible exhaust of your current jet system and measure it.
Can you state why you are considering replacing a steam jet system with a vacuum pump? If I had a similar choice, and no limitations, I probably try to do the opposite.
rmw