My thoughts:
1) I'm probably the world's biggest MathCAD fan, at least up to V15. It does offer some nice QC features. Namely, forced, consistent units and formula transparency.
2) I feel that the "Disaster Waiting to Happen" stuff is fear mongering and I'm a little embarrassed for PTC that they've taken that tack.
3) Most of the stats come from the accounting world. My brother started of as an accountant and I've witnessed him doing his thing. They take huge amounts of data, rotate it, flip it, sort it, and cross pollinate it in a matter of minutes with next to no checking. I'm not surprised that they have problems. Much of their data manipulation would be more appropriately handled in a database in my opinion. In summary, I suspect that there would be far fewer erros in our "template calc" applications. I've no problem with Excel being used in this way.
4) While a handful of errors have cropped up in some of our vetted Excel sheets over the years, I can't say that a single one has really led to any dire consequences. QC is always and for ever about less errors. In practical terms, it's never about no errors. I feel as though we've been batting a pretty good average with Excel so far.
5) Having managed some larger teams, my experience is that most hand calculations will be full of errors and there will be very little consistency between team members. Truly, I'd rather have everybody using the same spreadsheet, even if there is a small chance of a systematic error in that spreadsheet. You gotta pick your poison and I pick that one.
6) In my work, I use both Excel and MathCAD for template calcs. Most of my stuff is MathCAD and most of other people's stuff is Excel. I also use MathCAD for free form, project specific design notes which I love. Due to the transparent nature of MathCAD, we're also sometimes willing to use it for template calcs that haven't yet been properly vetted. If somebody needs to run a calc that already exists as somebody else's MathCAD sheet, it makes sense to give it a quick once over and then roll with it. That also serves as a check on the original which is nice.
I like to debate structural engineering theory -- a lot. If I challenge you on something, know that I'm doing so because I respect your opinion enough to either change it or adopt it.