Cs is the the equivalent lateral load factor.
The dynamic character of seismic loads is simplified to a horizontal force in the equivalent lateral load proceedure. Because the amount of force is dependent on the mass of the object (W), the code simplifies the calculation to be a certain percent of W. We call that Cs. Cs is dependent on five things:
Geography or simply the ground acceleration (Sds & Sd1).
The response modification factor (R)
The importance factor of your structure (I)
The approximate fundamental period of your structure(Ta, but also CuTa)
The long period (only valid for 05 ASCE 7 and later).