I would like to elaborate on Mike's point. I don't know the details of the structure and diaphgragm, but if the rafters bear on top of a CMU/wood wall/whatever, how does the shear force get from the diaphragm into the shear wall? How is the overturning force induced by the shear force at the top of the members resolved?
If it is a very shallow roof framing member, there are mechanical connectors capable of resisting this in-wall-plane shear force, but none that I know of for 2x12s. Or diagonal straps/braces depending on the force. But you have to check the numbers.
My answer is blocking, almost always does the job, cheap, hard to mess up. Yes you have to coordinate ventilation. There was a multi-page article a few months ago in Structural Design or something similar on this very subject, the only one I have ever come across... Yes I am in high wind country but even in low wind country how do these forces get transferred without blocking or diagonal straps?
Andrew Kester, PE
Florida