Yes. I've done many of these. The two trolley rails I designed were manually powered, but I suppose they could be electrically powered as well. It is the same as a monorail with one trolley, you just have to design the runway rail and supports for two. If you know the trolley dimensions, you can figure out where the wheels will land on the bottom flange and cumulatively add the localized stresses in those areas.
You will have multiple load cases and locations you have to design for. It will take multiple attempts to find the maximum stresses in your member. I utilized RISA 3D and their moving loads to accomplish this. If you have a simply supported monorail, it will be pretty straightforward; link them together and send them running down the runway. If you have a multi span beam, it might take multiple iterations to figure where the maximum locations of hoists are located at, especially if the hoists are rated for different load capacities.
You need to get the CMAA specifications put out by Crane Manufacturer's Association of America. That is invaluable. Use this for one or two trolleys. You should perform the calcs by hand first to make sure you know what you are doing.