Fahmed,
The pressure vessel design is based on calculating the minimum required thickness for a every component retaining pressure and that minimum thickness is obviously proportional to the design pressure. That is, the higher the design pressure is, the thicker is the minimum required thickness. The ASME code has made provisions for a reasonable engineering design, for the most common materials used in the industry. It has been established that the Division 1 method of design is most economical and sufficiently safe up to around 3000 psi. Above that pressure, the design method may not be as economical as it should be, hence a Division 2 method of design has been created, to help the design engineers, fabricators and end users to build a safe equipment, but allowing some thickness reduction in comparison with Division 1 by applying more stringent design/fabrication/testing requirements.
Nothing will prevent you designing and stamping your equipment subject of 5000 psi pressure to Division 1. However, it could be more feasible for you to take advantage of the Division 2 allowances.
This days, if in doubt, you can run some quick numbers on the major components of your vessels, to estimate if the design to Division 2 would be beneficial to you (or to estimate the losses if you will use the Division 1 instead of Division 2. I assume that you are using some PV Elite software or similar. As per the above, you could quote on the Division 1 basis, but you might not be competitive as the Division 2 fabricators.
cheers,
gr2vessels