Hi mtrehy, the orifice plate and flow manometer are the heart of a flowbench, and are probably the most difficult part to find information on when beginning a project like this.
The flow manometer just measures the pressure drop across a plain thin sheet metal orifice plate. The relationship between pressure and flow will always be square law. So if you double flow, pressure goes up four times. Triple flow, pressure goes up nine times. This relationship is exact for any sized orifice.
So what you do is make yourself a a flow scale in percentage flow. First you need to decide at what pressure you are going to use as the 100% flow reference pressure across your orifice plate. It can be any pressure you decide to use. A lot depends on your available blower pressure and flow. It takes a lot of horsepower and electrical power to generate high pressures and flows, so usually the orifice plate pressure drop will be considerably less than the test pressure across what you are measuring.
If your test pressure is going to be 28" of water, and your flow manometer 12" of water at 100% flow, your air blower must be capable of at least 40" over the desired flow range of the bench.
Now a 12" manometer scale will be a bit cramped, so you incline a much longer manometer tube so one end is twelve inches higher than the other.
It does not matter how long your scale is, or the angle of inclination you end up with, or the final orifice flow pressures you decide. The same square law scale is required.
So suppose you decide that your scale is going to be two feet long. At 100% flow the fluid goes two feet along the sacale. At 50% flow the fluid only goes six inches.
Remember doubling the flow (50% to 100%) causes four times the pressure drop (6" to 24"

. So you mark off your scale for all flows from say 40% to 100%.
The way you calculate the scale increments would go like this, (for 51%) 0.51 x 0.51 = 0.2601. And 0.2601 x 24" = 6.2424".
If your scale length was 500mm instead, it would be 0.2601 x 500mm = 130mm.
So your 50% division would be at 6" and your 51% division would be at 6.24". You just keep going up to 100% or even beyond. 101% = 24.4824".
I prefer metric myself. If you make your scale say 600mm,or 900mm, it is a lot easier to find accurately 301.5 mm for example than mark off some strange fraction of an inch.
You can use this same scale for any orifice plate, that you finally decide to use, and any orifice reference pressure, by simply tilting it the right amount.
The flow through an orifice plate in CFM will come pretty close to 13.55 multiplied by the square root of pressure in inches of water, multiplied by orifice diameter squared.
So if you have a two inch diameter orifice, and your 100% flow reference point is sixteen inches of water:
CFM = 13.55 x square root of 16" x 2" squared. Your orifice should flow 13.55 x 4 x 4 = 216.8 CFM
The actual flow you get might vary quite a bit because the edges of your orifice might be slightly rounded or have burrs. Also the air upstream needs to be fairly undisturbed. Also measuring the static pressure of a moving airstream is not all that easy either.
There is a very good book, Practical Gas Flow by John Dalton, ISBN 0947981330 it is a good read.
Cheers, Warpspeed.