Suggestions:
1. Supposing that you have more diversified sizes and variety of electrical equipment, then it may pay off to model and determine circuit breaker sizes via the following or similar software:
E.g. SKM, Inc. (DAPPER, A-FAULT, etc.), OTI, Inc. (ETAP), EDSA, etc.
These businesses have their web sites.
2. Less accurate approach is usually by hand with some estimations and approximations. Suggested reference:
Beeman D., "Industrial Power Systems Handbook," McGraw-Hill Book Co., Inc., 1st Edition, 1955
3. To provide more info, additional information is needed:
1. Load diversity
2. Motor load
3. Power factor compensation
4. Harmonics
5. Transformer nameplate data
etc.