Reduced shaft seal life. No quantitative guess as to how much. If shaft seals are desiged for 100psi, max, and are operated at 1250psi, maybe seal life will be reduced by ~90%. What is the original design life?
Control flow, not pressure, to control fan speed.
Do you know that the motors will, in fact, demand full system pressure capacity?
I'd recommend a parallel motor arrangement with individual flow controls to control motor speed. Maybe some thermal feedback to control motor speed.
Ted