Since C19 may have been the result of climate change forces, it is worthy of some discussion.
There is no evolutionary effect.
After all the nonbreeding population had gotten it, where else could it have gone? It was not ever going to dissappear on its own. The targets were never actively selected. It attacked all indiscriminately. Some targets survived better than others. Lockdowns and vaccines simply reduced the size and number of viable targets in the field, which also reduced the rate of ammo supply. You see in this game, ammo is supplied in proportion to the number of viable targets in the field, just like US drone strikes. That's why the curves are of lesser amplitude and of shorterer duration now. Ammo is depleting. However the delta variant may be a smarter bomb, which will probably be confirmed in short. The trajectory of C19 would have been different and much more of the original target would have been destroyed if left to its own devices, as it was only a matter of time before it reached all ages one way or another, if it was not suppressed. If it was not suppressed, the war would have been over in one informidable blitzkrieg. The outcome in regard to evolution did not change and the approval for 5-12yr olds today in the EU, as well as the various mandates for the still viable targets to remain at home, or get vaccinated, will reduce the target size even that much more. Hopefully those that cannot still take the vaccine can be protected until they can. This war will be over only when all viable targets are removed from the board.
The "Afganistan Solution" is guaranteed to have evolutionary impact, which has real potential for evolutionary advancement, but equal, if not greater, potential for complete failure, as it apparently takes only a small percentage of the uncooperative to really keep throwing spanners into the works by continuing to contribute to the wrong gene pool, i.e. the virus' gene pool, and allowing it to mutate until it hits just one of the right gene sequence that will take it past all known forms of resistance. Evolution works both ways. Do you bet on the human gene or the virus gene to survive. Can you tolerate the cost of the long term war taking it into the trenches, or would you prefer the surgical drone strike method. Maybe, just maybe, it might start attacking only the smart people. Then where would we be when the CC crisis finally hits?