Horizontal storage tank for highly purified water 1

[atah]

We are designing a highly purified water system for pharmaceutical plant. There will be a 20 cubic meter purified water storage tank. Due to space constraint, we planned to design a horizontal tank. Would like to know is this a common practice to have horizontal tank in a highly purified water system? What are the pros and cons of a horizontal tank compared to verticle one? Please advise.

Thanks.

 

[MedicineEng]

Define "highly" purified water. Is it injectable grade?
I can tell you that I have a horizontal water tank in my PW skid but but is just for oral dosage form use.

 

[quark]

1. Drainability of the tank can be a problem.
2. Cleaning may not be possible with spray ball and you may have to go for multiple nozzles.
3. You may have to go for higher dead volumes to avoid air ingress into the distribution system due to vortexing.
4. Occupies more floor space.

Before fixing the capacity, just check that you have atleast one volume change per day.

Regards,

 

[atah]

Thanks for all your advices. It's actually for PW with 1.3microS, 10cfu/100ml, and toc<500ppb, used for manufacturing of OSD and eye drop products. The storage tank will serve the PW loop, which is a ozonated cold loop (<20C). The loop will be about 500m long, with 30 PoUs. We still can't decide on the tank design and really appreciate fro your advices.

Thanks.

 

[atah]

Happy new year guys,

Would appreciate if I can have some more advice before we make the decision.

Thanks.

 

[MedicineEng]

As quark pointed out, horizontal tanks do have some issues. If you can choose, go for the vertical tank. We only chose the horizontal tank due to height constraints. Be aware of the issue of the volume change, it is important to avoid contamination growth and also because of the sanitizations of the system.
Just some remarks regarding your system:
-Forecast insulation in your loop since you will have it refrigerated, you can have condensation. It will also serve as man protection when you perform sanitizations to the loop
-500 mts is a quite long loop. Be aware of dead legs;
-Construction materials