In the past couple of years, we have seen a growing problem with broken stems on gate valve. I think the quality of valves coming from some countries is less than it had been in the past. With the stem in the vertical, a broken stem can result in a valve failing closed. With the stem in the horizontal, the valve would tend to fail in place if the stem breaks. You should consider the consequences of these possible failure modes. In some services, a valve that failed closed unexpectedly could cause disaster. If this is the case, I prefer a horizontal stem orientation. Otherwise, it’s just a mater of convenience and operator access.
Johnny Pellin