I would approach this change very cautiously. There is a HUGE difference in the quantity of sulfide inclusions when you go from ~ 0.020% S to anything greater than > 0.040% S. This is not a drop-in replacement. You definitely need to evaluate this from both a product perspective and a processing perspective. Fatigue life is the most concerning aspect, both under bending and under rolling contact. You need to test this, and not just with 1 or 2 parts-- you need something that would be statistically significant. The processing concern is with induction hardening of highly included steels. They are not as forgiving, so be careful with scan speed, quench intensity, etc. If this is high volume production, then process a lot of parts, say 1000 pieces, before making any final determination on processability. Look for cracks on the surface, and cross-section the parts to make sure there are no sub-surface defects.