Manually.
You can test this out yourself. Do a simple cantilever column with a mass on top. Use a formula to calculate the drift by hand (deflection of cantilever beam with a concentrated load at the end), and compare it to the seismic drift you get in ETABS. You might have to fugde a diaphragm to get this to work, but it should work as long as all members are pinned and you only have one fixed column.
Another way to test it is to vary the amplification factor. You'll see that no matter what you do, the drift will be the same.
If anyone knows why ETABS asks for an amplification factor, I'd love to know. I don't see it doing anything, anywhere.