If the loads are mainly as in your scheme lateral loads (wind, earthquake) there is scarce thing not common to the design of whatever the buildings. If the worrying loads are of dynamic nature, things start to be more complicated because dynamic analyses are less common, and if you want to make a static model as a substitute will need some reliable source about the equivalent forces imparted, that if small maybe you can obtain, but it is unlikely you can obtain them for other than at ground level for more relevant machines, since interaction with the structure becomes paramount. So machines able to noticeably put in vibration the buildings and with some tying structure in between are likely to put in high risk the durability of the connections of the bridging structure, if not subjecting the whole structure to significant compression to risk of buckling, or failure of the receiving columns. So the first thing to examine is if you have a dynamic analysis where the loading must be described along time or not, in which case what we ordinarily do would be enough to describe the major problems at hand.