There are two that I can think of:
Volume. See the intersection design chapter of AASHTO PoGDoHS (Green Book). It's based on percentage of left turn traffic, and opposing volume.
Crash history. If people waiting for a gap in traffic to make a left turn are getting rear-ended, a left turn lane will help. You can expect up to 48% crash reductions at 2-way stop controlled intersections. Crash reductions at signals are lower. There is a summary of this study on the Turner-Fairbanks highway lab website.
Or you could require a roundabout. <grin>
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