I know of no explicit limitation in ACI. With significant angular changes, I think that one would have to pay some extra attention to the design and detailing of the intersecting beam joint and the effects of torsion resulting from frame action. Without being able to point to any literature or research, I think that I'd start to be concerned beyond about 30 degrees.
I like to debate structural engineering theory -- a lot. If I challenge you on something, know that I'm doing so because I respect your opinion enough to either change it or adopt it.