Lblopez,
Did you check the "Help" section of Visual Flow for their definition of K? In their documentation they should have an equation for pressure drop with K defined. If not, call the person in your company that gives technical support for that software or call Visual Flow's technical support or search their website.
If not, EGT01 did an excellent job above. Be careful with units (SI or English)! Different units will change the value of K.
You can estimate the pressure drop (dP) of a heat exchanger with HEXTRAN. Let's say you want to calculate K for the tube side of a particular exchanger. For example, let's say HEXTRAN calculates the dP of the tube side of this particular exchanger at 5 psi. Now you need to take the dP (5 psi) from the heat exchanger evaluation and use it to characterize the heat exchanger as a fitting or pressure drop element in Visual Flow with a K factor. So, use EGT01's equation for K:
K = dP * d^4 / (0.00001799 * rho * Q^2).
dP = 5 psi
d = the inside diameter of the water piping to and from the tube side of this particular exchanger used in Visual Flow
rho = the density of the water to and from the tube side of this particular exchanger used in Visual Flow, lb/ft3
Q = flow of the water to and from the tube side of this particular exchanger used in Visual Flow, gpm
Take the calulated K and use it in Visual Flow.
*IF* the flow and density of the water to and from the tube side of this particular exchanger used in Visual Flow CHANGES as your simulations in Visual Flow approach reality, you'll need to re-calculate a K for the tube side of this particular exchanger. It may take a few iterations to a converged solution.
Good luck,
Latexman