Generally speaking, for a new design, you should be able to get 100psig on a 3 stage centrifugal - I've assumed polytropic eff of 80% on all 3 stages, which should be possible for the volume rates you've got. With a 4 stage, it shouldnt be a problem. Compression ratios I get are 2.6 on stage 1 and approx 2.2 on stages 2 and 3. Intercooler temp is 45degC for all 3 stages, which should be possible for most climes. For an existing machine, how do you plan to "delete or make do without" 1 or 2 stages on a 5stage machine? Bypassing one or more stages by external piping modifications can result in rotor imbalance.