Yes, and here is the reason. The heat treatment for AA 6061 T6 is as follows;
Solution treatment 960- 1075 deg F
quench in water
Artificial Age (Precipitation heat treatment)
@ 350 deg F for 8 hours
This information was obtained from ASTM B597 -Standard Practice for Heat Treatment of Aluminum Alloys. This would apply to various shapes; extruded tube, rod, structural shapes....
The reason I provided the background information on 6061 T6 was to show that the solution treated/artificially aged aluminum alloy will loose strength upon exposure to any subsequent temperatures above 350 deg F. At 250 deg C (482 deg F) you are well above the precipitation heat treatment temperature and, as such, would soften the T6 material to a different temper/strength upon exposure for 12 hours at temperature.
For additional information, the MIL-HDBK-5H has a section on Aluminum alloys, and more specifically mentions exposure of heat treated aluminum alloys to elevated temperatures (3.1.2.1.8) that can degrade strength over time.
The reason for the decrease in strength and hardness is because of exposure to temperatures above 350 deg F (the artificial aging temperature), which causes the precipitates from artificial aging to coarsen over time at temperature. The plus side to carbide coarsening is increased ductility and toughness for the alloy.