A Wheatstone bridge is a combination of four resistors connected in a ring. This results in four junctions, which I will call 1, 2, 3 and 4. Power is applied across junctions 1 an 3. Voltage is measured across junctions 2 and 4. If all resistors are equal the voltage will be zero. if one resistor has a slightly different resistance, then a voltage will be produced across junctions 2 and 4. This voltage will always be a fixed ratio to the applied voltage. A special circuit is used to measure this ratio. This makes the circuit independent of the applied voltage.
Typically one resistor is replaced by a strain gauge. The ratio is then a measure of the amount of strain applied.
Hope this helps.