There are several factors that come into play. A few big ones that I can think of that are mainly combined GVW related:
- engine cooling and longevity
- trans torque capacity, cooling and longevity
- axle cooling and longevity
- brakes (depending if trailer has brakes, could assume no for worst case scenario)
(and don't forget OEM bragging rights in the case of PUs)
I can't find the article now, but I read one a couple months ago that discussed how SAE came out with a new differential oil viscosity mostly for 1 ton trucks. The thicker oil was eating into the fuel efficiency and the thinner oil wasn't passing durability tests.
ISZ