I've only just looked at this forum, so sorry for the delay in replying. Actually, by changing the operating pressure from 24 psig to 35 psig, you are changing nothing in relation to the need for pressure relief. To define if you need pressure relief (and to size it), consider this. You are using a vaporiser, right? So, you must have a heating element (Steam, electric, hot oil...). This has a maximum temperature associated with it - say steam at 300°F max. for the sake of argument. Then, the HF will have a certain vapour pressure at that temperature. If that vapour pressure exceeds the design pressure of the vessel, then you MUST have pressure relief, for the event that the normal outlet path is blocked, e.g. due to a closed valve. This is, however, just one contingency, consider the HF feed pump/system (unlikely to be the worst case scenario, but could be, e.g. if using N2 overpressure), fire case etc. etc. Make a list of every credible thing that can go wrong and design any relief for the worst case.... Also consider vacuum - what if the outlet is blocked, so the heating element goes off (Possibly due to a control system because the outlet is blocked)? HF vapours condense --> vacuum. If designed for full vac., no problems, but if not, you may need a vacuum breaker. If there is no credible case for any pressure or vacuum relief, then you don't need one (Unless specified by the vessel code - see above comments!).