Konrad,
Since progression is an essential variable for welder qualification, a test assembly is required to represent each of those conditions. If it were plate and two coupons were required, you would need two coupons with uphill progression and two with downhill progression. When testing a welder on pipe, if four coupons are required, you would need four for each progression.
I'm not aware of a paragraph which spells this requirement out, but, the key is QW351 'a welder shall be requalified whenever a change is made in one or more essential variables'