Bucz48;
Your question is too broad, you need to be more specific regarding base materials and filler metals. The gases used for GTAW are not optimized to increase hardness or affect base metal heat affected zone hardness. This had more to do with weld metal dilution, preheat requirements and filler metal selection.
There are standard gas mixtures to provide suitable weldability, depending on weld joint position and desired toughness (with or without PWHT). Gases will affect depth of penetration and porosity with the GTAW process.