More details, better answers.
As this is a cost/benifit calculation, NOT a pure technical one, we need a lot more information. 'High pressure process conditions' in a forum for 'pipeline and fluid Mechanics' can be valves for anything from gas, water, oil to anything else. (Not only petroleum related as some always seems to assume.) Pressure class and diameters might also vary widely.
From my experience you may note down some general points:
Smaller sizes, not very often operated, non critical for continious operation, repairable without demounting from pipeline
larger number equal valves: all separately lean in favour of welding ends.
We must take into consideration the requirement for continous uninterrupted operation time, cost for repair and shutdown. I have supplied high pressure class valves up to several tons. (Hydroelectrical and drinking water pipelines if you wonder). For high pressure class valves of larger dimensions the process of welding in place, and not at least removing and replace, would be costly and highly impractical.
End types regarding to class, size, fluid and precess requirements and cost have to be considered for each case.