Current high efficiency domestic A/C units already use a VFD on the air handler motor to provide variable speed and very quiet operation. The compressor would require a serious VFD because of its starting current, so it's typically cycled with a contactor.
My experience says the current limit to durability is that VFD controlling the air handler motor. Worse, the aftermarket is not supplying replacements. The VFD is built into the motor, and it's clearly more profitable to just supply replacement air handlers, which is all anyone will sell.
I looked at replacing the VFD in my penultimate air handler with an industrial unit. One, it doesn't have the backpressure sensing logic built in, and two, VFD manufacturers, in the fine print, suggest replacing all the capacitors after five years anyway, so they clearly haven't got a handle on what's expected for domestic A/C durability.
Mike Halloran
Pembroke Pines, FL, USA