For a given pump size and impeller style, the impellers for a multistage pump are usually identical, so the efficiency is the same.
In your case, you are comparing a 1 stage offering to a 2 stage offering. The motor hp should be approximately the same, because the work being done is the same. There is a trade off in selections - the single stage pump must be a bigger pump, to get x head. The two stage pump would be a slightly smaller pump (assuming the speeds are the same).
The differences will probably show up in NPSHr, min level for vortexing, etc. You may prefer a smaller, 2 stage pump, due to physical size, or you may prefer a 1 stage. Depending on the manufacturer's costing, maybe a smaller 2 stage is less expensive than a bigger 1 stage, or maybe the reverse.
Depending on your application, look at the min operating level and NPSHr, then the physical space requirements, to see if either one will fit. One thing about VT pumps - there are so many possible combinations that often each application engineer will come up with a different solution to your problem.