mageshk
In top down assy, u fix some points first like (as in a bike) the wheel centres, swing arm axis, etc. now u create a skeleton model of curves with these points. with this as the first model in the top down assy, u can create other components in the assembly (atleast partialy). here u can create layout design which will help in studying the jounce and rebound conditions.
As mhendler said, bottom up assy is building up the assy with models ready already.
thilak