Fred,
The initial problem with the 5,000 psi system in the Osprey was thay the high pressure kept bursting gaskets and seals. This set the program back a considerable amount of time. You can't just put 3,000 psi fittings on a 5,000 psi system, and they found this out rather quickly when they ended up with hydraulic fluid all over the place.
On a very large vehicle (A380), the higher pressure system can save you weight, because your hydraulic lines can become smaller in diameter, and you need to carry less fluid. You DO however have to beef up the fittings, gaskets and seals.
On a smaller aircraft, the amount of weight you save by increasing the pressure isn't significant, because you just don't have nearly as much hydraulic tubing on the vehicle (as you would in an A380 sized machine).
There is a reason that 5,000 psi systems are not typically used in small aircraft. Typically, you do not need 5,000 psi to actuate flaps, landing gear, etc. In the JSF however, I believe their thrust vectoring system is hydraulic, and they have a need for high pressure systems.
Like anything in the aerospace world, you are going to pay for performance. The Osprey designers tried to use cheaper low pressure hardware on a high pressure system to save money, but it ended up back firing on them. Rather than replacing the system with low pressure configuration (very expensive), they upgraded the hardware to handle the higher pressure. This means more cost per airplane.
The vortex ring is a fundamental problem in all hovering aircraft, even the Harrier. Re-ingestion of rotor wash will drop you like a brick. There is limited amount of time you can hover, and the time increases as altitude increases (up to I believe 4,000 ft).
Regards,
Grant Wittenborn
Aerospace Engineer