TIP: System curves are usually not perfect parabolas. Well, maybe you can get one in labratory conditions, if you have one product at uniform temperature. You could get a perfect parabola.
First one I can think of is when transitioning from laminar to turbulent flow. That produces discontinuities.
There's lots of non-Newtonian fluids, which give system curves that are radically non-parabolic. Catchup, Sulfur, slurries...
Classic examples would be for,
1.) Hot heavy Orinoco crude pipeline, which exhibits some degree of non-Newtonian characteristics and it also cools as it is pumped from the oilfield down to a marine termainal on the coast, so viscosity changes along the length of the pipeline. It can also transition from turbulent to laminar somewhere along that length as well, or
2.) For a liquid sulfur pipeline. Liquid sulfur is highly non-Newtonian and worse at some temperatures than others.
3.) Both of the examples are complicated by cooling as they flow down a long pipeline.
4.) A product pipeline with more than one product being transported at any given time of course would have a big discontinuity at the batch interfaces. Many product pipelines can have several batches contained at any one time. That would be a system curve that continuously varies with the density and the position of the batches.
5.) Two-phase flow varies with %gas to % liquid ratios
6.) A pipeline that must switch between packed flow and slack flow at some flowrate,
Let's see, how much more thinking time do I have left???
Going the Big Inch!