Sizing a fan for pressurization is one of the harder calculations to perform so I'm sorry they assigned this to you. It's hard because you have to rely on the tightness of the room but you don't have a ton of control over it with your scope.
I would ask whoever is designing and installing the room to make it as tight as they possibly can. Then you can provide a supply fan and relief damper; even a manual relief damper should work fine.
I am also a little blown away by the cooling load of that equipment. Double check that but maybe your company does way bigger projects than I've ever worked on. With that much cooling and flowrate, you'll want to think about the location of your supply outlets and return inlets. Place return inlets away from doors/windows/walls if possible. You don't want a negative pressure next to a door.
You can get some rule of thumb numbers for room tightness (air leakage area) from 2015 ASHRAE HVAC Applications Manual, pg 53.7, table 2.
Then it looks like you can use Equation 11 from the same page of the manual for the CFM equation.
V = 776*C*A*(sqrt((2*deltaP)/rho))
V = volumetric flow in CFM
C = flow coefficient (see pg 53.5)
A = flow area (leakage area), square feet
deltaP = pressure difference, inches of water
rho = gas density in path, lb/cubic ft
Hope that helps.