As far as *compatability* goes, there is not much difference if you are using late binding, and just optimizations, if you are using early binding.
There are of course, the usual 'obsoleted' methods (replaced with a higher numeric count), such as "Entity.Select2" is replaced with "Entity.Select3",
the "AssemblyDoc.ReplaceComponents" call now requires a different call altogether, as well as the Block Definitions calls (but I think they are much better)
When you parse the feature manager tree, you will find 2 new
'features' ... Solid Bodies , and Surfaces. The Surfaces feature is hidden and I have been unable to 'unhide' it.
These are both in respect to the ability SW now gives for 'multi-lump' bodies.. (like floating pieces of solids)
If you find more than one 'solid body' while parsing the feature manager, the model may not be completed, or it may have errors.
And if you usually rely on fancy Equations/design tables to
harness in your configurations, you may find the "Macro Feature" a pleasant suprise.