Bradley,
Ok, make sure the box does not have an onboard modem. If it does disable it in the BIOS. Also, check bios setting to confirm that the com/serial port you are using is enabled, and set up correctly. Then make sure the com's are set up properly in windows. Now, with that said. Do you have the external power supply for this unit? The way that it was explained to me is that, some serial ports run a bit more power than others. If the box the unit in question came from had a stronger com port then that could be a reason for the unit not being detected on the new box. The power supply for one of these should jump into the com lead for the spaceball. The 2003's that I have will not run w/o an external power supply on any of the computers I have. If you do not have the power supply, I would call 3Dconnexion tech. They sent me a power supply for a serial model for free. I would assume if you were nice they would do the same for you.
Really, if it worked on the other computer, and it never got "dropped" when it was moved from one to the other, then outside of a com port conflict or power supply issue there is no reason it should not work. I really suspect a com port issue before power supply on the newer unit you have. Make sure there is nothing else in the system using the com port. If you had some serial device installed and removed it w/o uninstalling the drivers for it then possibly that is what is causing the conflict. The drivers for that "other" device may still be mucking up the com port for the spaceball. The 4000FLX model is hella newer than mine so they may not require the external power supply. I don't really know. If possible, I would call this guy:
Contact for Technical Support:
Ken Denton
Tel: (888) 247-9545
Fax: (248) 331-1399
Email: ken_denton@3dconnexion.com
He was a big help to me. As well as the person that saw to it that I got a free power supply to see if that would get the unit working. I was very impressed by the level of service that I received from him.
Hope this helps,
Sean F
seanf@newing-halll.com
1 2 many l's in email