pogoGo - first, welcome to eng-tips.com.
Excellent questions. The answer that jte provided to your first question is sufficient.
Regarding your second question about the reasoning for the load case combinations and load factors thereof; first I would point you to ASME PCCPTB-1. There are some very good explanations in there. A summary is that we are trying to be analogous to the Structural Code ASCE-7 and we take guidance from their load factors.
For Protection Against Local Failure - you will notice that the thermal loads are also neglected from the load case combination, as well as the live loads that you pointed out. That was a judgement call by the committee. When situations such as yours arise, we concluded that, if the design engineer considers it important, then they are empowered to include them by 1.1.1.2, and the User should include them in the UDS by 2.2.2.1(h) (in which case they do form a mandatory part of the calculations).
The Code represents a minimum standard, but should not be considered the final arbiter of all things pressure vessel-related, because there are simply too many possible situations that cannot be foreseen. If, in your opinion, your live loads are significant and important, then I would suggest, perhaps as a start to reclassify them as dead loads. If that causes problems, then I would add some factored live loads to Required Factored Load Combination (1), such that it is consistent with Required Factored Load Combination (2). And, by all means, feel free to add some factor of L into the Required Factored Load Combination for Protection Against Local Failure. There is no prohibition on being more conservative than the Code.