Most any elastomer will cold-flow and conform to microscopic (or larger) surface irregularities if it is compressed against a surface for a long time. We have all had to scrape gaskets.
The possible consequence of that in a safety-relief valve would be that the valve would not pop at its calibrated relief pressure.
If the seat/seal is designed properly the elastomer o-ring of choice would not be so highly loaded that it would bond against the surface of the nozzle. Marketing buzzword: "Controlled Compression". The disc is designed to seat against the nozzle with metal-to-metal, and the elastomer seal fits in a cavity in the disc so it is gently squeezed against the surface of the nozzle. The Parker O-ring handbook has specific guidelines for the appropriate amount of compression.
It's probably appropriate to remember that the SRV is only there to protect personnel and property. If the operators are doing their jobs correctly and there is not an equipment failure, then the SRV will never pop. If the valve does lift in response to an overpressure and the o-ring is destroyed, the valve will reseat but it will leak. That's OK, because it has saved the component from overpressure and it's time to shut down the system and verify that nothing was damaged by the pressure excursion.
Viton, Hypalon, Neoprene, Buna-N are all used for hydrocarbons and there are individual selecton criteria-most notably the maximum service temperature each withstands.