There is no standard saying "thou shall not oversize PSVs", but API 521 has an excerpt saying:
sect. 5.8.2.2
"These studies verified that vapors released from PRVs through their individual stacks are safely dispersed even when
the valves were operating at only 25 % of their full capacity, which corresponds to the reseat level of the valves."
One could argue that from this, one is not following recommended practice if a PSV's sizing case is less than or equal to 25% of full capacity. Also note that a PSV's rated capacity has a 10% conservatism factor included, so this is then equal to 27.78% of available area, and I've heard PSVs requiring less than 30% of available area are generally considered oversized.
For the minimum size 3/4"x1" PSVs, they have much less force/weight flopping around, so oversizing one of these valves is not a concern. On the other hand, having a 4L6 PSV (2.853 sq. in.) where only a 2H3 (0.785 sq. in.) is required is pretty questionable... personally I would recommend reducing PSV size for this instance, but API does not address this issue and the costs may not be justified. In general it is very difficult to reduce PSV size unless clearly justified, as having an undersized PSV is much worse than an oversized PSV, and all PSVs are oversized to some degree.
Installing multiple PSVs to avoid chattering is a good practice, but not that common from my experience, probably because it is slightly cheaper. I'm actually quite curious why 2 PSVs aren't used more often instead of only 1 to protect a vessel. Seems like two smaller weight PSVs would make them easier to install, cheaper, and easier to maintain. Also for spared service, one could have 3 half size PSVs vs 2 full size PSVs.
In terms of weight, a 300# RF 4L6 weighs ~220 lb while a 2H3 weighs ~65 lb. The thought of that amount of weight chattering around makes me uncomfortable.