After all the above excellent comments (even some are not so accurate, they all give good points to think about). I can add...
The pressure is quite high, don´t dare to do it without experienced knowledge. You could be in a point that integrally reinforced nozzles and FEA would be recommended. (Worst if pressure fluctuations or vibrations are expected.)
When you start to make vessel designs go to the welding shop you think will take care of your jobs, observe the procedures and ask, some design rules about RFs are better understood or even followed "by default" when you see what are the real practices and shop resources. Many times the welding procedures and skill define the type of joint the joint factor, the size of the reinforcement, etc.
ASME reinforcement rules are based on pressure mainly, but external loads on nozzles implies even more complicated and sometimes more important design analysis (WRC 107, FEA, etc.).
Don´t look your vessel just as an ASME code item, look it first with the optic of a more general code or standard that may apply; a local safety code, an API, NFPA, OSHA, Factory Mutual, a construction code, etc. That will clarify if you are able to design PVs. Sometimes you see experts on vessel design that result to be not so expert since they forget basic requirements.
Good luck.