You also have to consider the fire rating of the pipe as it passes through any fire separations - even if it's filled with water, the Code Officials choke on the flame and smoke spread rating of PVC, so if you are penetrating fire separations, you may have to go back to metal pipe for the penetration then back to plastic.
Another issue is the solvent welding of the pipe, an incident occurred on one job I know about where the fumes from the solvent were flammable and touched off an explosion inside the pipe when a local spark near the open end of the PVC pipe ignited the fumes that were trapped inside the pipe. This was in a length of about 100 meters of 300mm schedule 40 PVC pipe. So if you do use solvent welded joints, make sure the Trades ventilate the pipe during assembly.
It's still a fair cost saving vs steel pipe, even if the steel pipe is mechanically joined (grooved locking clamp joints).